ISOOROTIC ACID ETHYL ESTER
5-carbethoxyuracil crystalline
CAS: 28485-17-8
Molecular Formula: C7H8N2O4
ISOOROTIC ACID ETHYL ESTER - Names and Identifiers
| Name | 5-carbethoxyuracil crystalline |
| Synonyms | 5-CARBETHOXYURACIL 5-Carbethoxyuracil Ethyluracil-5-carboxylate ISOOROTIC ACID ETHYL ESTER Methyl uracil-5-carboxylate 5-carbethoxyuracil crystalline ethyl 2,4-dihydroxypyrimidine-5-carboxylate ethyl4-hydroxy-2-oxo-1,2-dihydropyriMidine-5 ethyl 4-hydroxy-2-oxo-1,2-dihydropyrimidine-5-carboxylate ethyl 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Ethyl uracil-5-carboxylate 5-Carbethoxyuracil |
| CAS | 28485-17-8 |
| EINECS | 249-053-3 |
| InChI | InChI=1/C7H8N2O4/c1-2-13-6(11)4-3-8-7(12)9-5(4)10/h3H,2H2,1H3,(H2,8,9,10,12) |
ISOOROTIC ACID ETHYL ESTER - Physico-chemical Properties
| Molecular Formula | C7H8N2O4 |
| Molar Mass | 184.15 |
| Density | 1.344±0.06 g/cm3(Predicted) |
| Melting Point | 232-235°C |
| Boling Point | 398°C at 760 mmHg |
| Flash Point | 194.5°C |
| Vapor Presure | 6.66E-07mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | White |
| pKa | 7.17±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.504 |
ISOOROTIC ACID ETHYL ESTER - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| HS Code | 29335990 |
ISOOROTIC ACID ETHYL ESTER - Introduction
5-carbethoxyuracil crystalline(5-carbethoxyuracil crystalline) is an organic compound with the chemical formula C9H10N2O4. It is a white crystal and has a relatively stable nature. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystal
-relative molecular mass: 206.19g/mol
-melting point: 189-191 ℃
-Solubility: Soluble in ketones, alcohols, chloroform and dichloromethane, slightly soluble in water
Use:
- 5-carbethoxyuracil crystalline is often used as an intermediate in organic synthesis. It can be used in the synthesis of folic acid analogs and other pharmaceutical intermediates.
-In the field of medicine, it is also used to synthesize compounds related to anti-tumor activity.
Preparation Method:
5-carbethoxyuracil crystalline can be prepared by the following steps:
5-bromouracil was obtained by the reaction of-uracil and bromoacetic acid.
-5-bromouracil reacts with ethanol to form ethyl uracil -5-acetate.
-Finally, the ethyl uracil -5-acetate is subjected to a deprotection reaction to give the 5-carbethoxyuracil crystalline.
Safety Information:
- 5-carbethoxyuracil crystalline is considered relatively safe under general conditions. However, proper laboratory safety procedures must still be followed during handling and use.
-Avoid contact with skin and eyes. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during use.
-Store the compound in a dry, cool place away from fire and flammable substances.
Nature:
-Appearance: White crystal
-relative molecular mass: 206.19g/mol
-melting point: 189-191 ℃
-Solubility: Soluble in ketones, alcohols, chloroform and dichloromethane, slightly soluble in water
Use:
- 5-carbethoxyuracil crystalline is often used as an intermediate in organic synthesis. It can be used in the synthesis of folic acid analogs and other pharmaceutical intermediates.
-In the field of medicine, it is also used to synthesize compounds related to anti-tumor activity.
Preparation Method:
5-carbethoxyuracil crystalline can be prepared by the following steps:
5-bromouracil was obtained by the reaction of-uracil and bromoacetic acid.
-5-bromouracil reacts with ethanol to form ethyl uracil -5-acetate.
-Finally, the ethyl uracil -5-acetate is subjected to a deprotection reaction to give the 5-carbethoxyuracil crystalline.
Safety Information:
- 5-carbethoxyuracil crystalline is considered relatively safe under general conditions. However, proper laboratory safety procedures must still be followed during handling and use.
-Avoid contact with skin and eyes. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during use.
-Store the compound in a dry, cool place away from fire and flammable substances.
Last Update：2024-04-09 21:00:56
